For treating fibromyalgia in children ages 13 to 17 years old, the recommended Cymbalta dosage is 30 mg once a day. If you miss a dose of Cymbalta, take your missed dose as soon as you remember. This may raise your risk for side effects from the drug. This can include setting an alarm on your phone or downloading a reminder app. A kitchen timer can work, too.
Cymbalta is meant to be used as a long-term treatment. To help lower your risk for these symptoms, your doctor will gradually reduce your dosage over time. This is known as a drug taper. If you have additional questions about your risk for withdrawal or dependence with Cymbalta, talk with your doctor.
Cymbalta stays in your system for about 3 days. Cymbalta may also be used off-label for other conditions. With this condition, you may feel sadness, loss, or anger that interferes with your daily activities. Clinical studies have shown Cymbalta to be effective for treating depression. One study compared daily use of Cymbalta with a placebo a treatment with no active drug.
Almost everyone experiences anxiety at some point. However, you may experience extreme feelings of anxiety, or anxiety that lasts longer than 6 months. If these feelings interfere with your daily life, you may have an anxiety disorder. People with GAD have excessive anxiety that can occur frequently. Symptoms of GAD may vary but can include:.
One clinical study involved adults with GAD. Researchers first gave everyone Cymbalta for 26 weeks. People whose condition improved with the drug were then randomly chosen to either keep taking Cymbalta or switch to a placebo. A placebo is a treatment with no active drug.
They used increases in these scores to determine when someone in the study had a GAD relapse. The researchers compared how long it took for people using Cymbalta to have a GAD relapse compared with people taking a placebo. These results show that people taking Cymbalta had reduced anxiety symptoms for a longer period of time than people who took a placebo. Cymbalta is FDA-approved to treat pain from diabetic neuropathy nerve damage.
Diabetic neuropathy is a common condition in people with type 1 and type 2 diabetes. People with diabetes have high levels of glucose sugar in their blood. Over time, having increased glucose levels can cause nerve damage. Symptoms of diabetic neuropathy include numbness, pain, tingling, or weakness in your hands or feet. Clinical studies have shown Cymbalta to be effective for treating pain from diabetic neuropathy. Researchers in one study randomly assigned adults with diabetic nerve pain to take either Cymbalta or a placebo every day for 12 weeks.
They assessed pain again after the study to compare how Cymbalta and a placebo affected pain. Cymbalta is FDA-approved to treat fibromyalgia. This is a chronic condition that can cause:.
Fibromyalgia is often misdiagnosed and can be difficult to treat. Clinical studies have shown Cymbalta to be effective at treating fibromyalgia. One study compared Cymbalta with a placebo in adults with fibromyalgia. Before the study, these adults had an average pain score of 6. People in the study took either Cymbalta or a placebo every day for 6 months. The researchers then measured their pain scores again to see if there was any improvement. Cymbalta is FDA-approved to treat chronic musculoskeletal pain.
This refers to pain in the bones, muscles, ligaments, nerves, and tendons. Chronic pain is pain that lasts for more than 3 to 6 months. Clinical studies have shown Cymbalta to be effective for treating chronic musculoskeletal pain.
These studies involved adults with chronic low back pain or chronic pain caused by osteoarthritis a joint disorder that causes swelling and pain. In one study , adults with chronic low back pain took either Cymbalta or a placebo every day for 13 weeks. Before the study, people rated their pain on a scale of 0 no pain to 10 worst pain possible.
The researchers had people rate their pain again at the end of the study. Clinical studies have shown Cymbalta to be effective for treating these conditions in children. Cymbalta belongs to a class of medications known as serotonin-norepinephrine reuptake inhibitors SNRIs. It affects your levels of both serotonin and norepinephrine. SSRIs, on the other hand, only affect your serotonin levels.
Controlled substances are medications that could cause either physical or mental dependence. With dependence , your body needs the drug to feel normal. The Drug Enforcement Administration DEA sets limits on who can make, possess, and use medications that are controlled substances.
However, Cymbalta could cause withdrawal symptoms if you stop taking the drug suddenly. Addiction is different from dependence. Over time, someone with addiction needs more and more of a drug to feel its effects. This is because the drug affects your central nervous system CNS. If you have questions or concerns about your risk for dependence with Cymbalta, talk with your doctor.
Cymbalta is approved to treat mood disorders, such as depression and anxiety. Because it affects your mood, some people report feeling calm or as if their mood is boosted while taking the drug. If you have questions about how Cymbalta may affect you, talk with your doctor or pharmacist. This was one of the more common side effects of the drug in clinical studies.
In the studies:. If you have questions about side effects from Cymbalta, talk with your doctor or pharmacist. You may wonder how Cymbalta compares with other medications that are prescribed for similar uses.
Here we look at how Cymbalta and Lexapro are alike and different. Lexapro contains the active drug escitalopram. Lexapro belongs to a class of medications called selective serotonin reuptake inhibitors SSRIs. Both types of drugs are commonly used as antidepressants. Cymbalta comes as capsule that you take by mouth. Cymbalta and Lexapro have some similar side effects and others that vary. Below are examples of these side effects. This list contains 10 of the most common mild side effects that can occur with both Cymbalta and Lexapro when taken individually :.
These lists contain examples of serious side effects that can occur with Cymbalta, with Lexapro, or with both drugs when taken individually. The use of Cymbalta and Lexapro in treating depression in adults has been compared in a meta-analysis. A meta-analysis is a type of study that looks at the results of numerous clinical studies to see if there are any consistent results across the studies. In this meta-analysis , researchers looked at 16 different clinical studies that compared Cymbalta to other antidepressants, including three studies that compared Cymbalta with Lexapro.
The researchers found the two drugs to be similarly effective for treating depression. Cymbalta and Lexapro have also been compared in a meta-analysis for treating anxiety in adults. The researchers looked at 41 clinical studies involving a total of 11 antidepressants, including Cymbalta and Lexapro.
They found Cymbalta and Lexapro to be similarly effective for treating anxiety. According to estimates on GoodRx. Lexapro is available as a generic drug called escitalopram. Cymbalta and Effexor XR are prescribed for similar uses. Here we look at how these drugs are alike and different. Effexor XR contains the active drug venlafaxine ER. Duloxetine and venlafaxine ER both belong to a class of medications known as serotonin-norepinephrine reuptake inhibitors SNRIs.
This medication class is commonly used as antidepressants. Your Journey Family Members and Caregivers. Your Journey Identity and Cultural Dimensions. Your Journey Frontline Professionals. Get Involved Become a Fundraiser. Get Involved Awareness Events.
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Duloxetine Cymbalta. Know the warning signs Learn the common signs of mental illness in adults and adolescents. Mental health conditions Learn more about common mental health conditions that affect millions.
Missing doses of duloxetine may increase your risk for relapse in your symptoms. Caution is advised with breastfeeding since duloxetine does pass into breast milk. Symptoms of your condition that bother you the most If you have thoughts of suicide or harming yourself Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, but others may require changes to the medication.
Any other psychiatric or medical problems you have, including a history of bipolar disorder, kidney or liver disease All other medications you are currently taking including over the counter products, herbal and nutritional supplements and any medication allergies you have Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these different treatments work with the medication.
If you are pregnant, plan to become pregnant, or are breastfeeding If you drink alcohol or use drugs How Should I Take Duloxetine? Duloxetine is usually taken 1 or 2 times per day with or without food. The capsule should be swallowed whole. We have only included the most common ones here.
Please look at the leaflet inside your medicine box, or ask a doctor or pharmacist, if you want to know whether you are getting a side effect from your medicine. If you do get a side effect, please think about reporting it via the 'Yellow Card' scheme. We use cookies We use cookies on this website to store user preferences, aid in accessibility and analyse our traffic.
Read our cookie policy. Accept all cookie usage. Update cookie preferences. Open guide menu Skip to guide menu. I am a young person I am a parent I work with young people. Open site search Open main navigation. View shareable links View Basket : 0 items. Guide Menu for Duloxetine. Hide Show guide menu. Guide contents jump to section About duloxetine Duloxetine and everyday life Uses, warnings, safety and side effects About this information More information and advice.
About duloxetine. Please note. Always talk to your doctor about your situation and whether this medication is for you. Thinking about trying medication? Read our guide. How duloxetine works. Duloxetine is a serotonin and noradrenaline reuptake inihibitor SNRI. Noradrenaline is sometimes known as norepinephrine.
This increases the amount of serotonin and noradrenaline, which helps treat the symptoms. Duloxetine and everyday life. Frequently asked questions. How long does it take to start working?
What effects will it have on my body? It is very difficult to know how it will affect each person who takes it. Talk to your doctor about this if it worries you. Should I tell my family and friends I am taking it? Will it affect my sleep? It can also give you sleep problems, including unusual dreams. Can I drink alcohol, take street drugs and smoke while taking it?
Alcohol You can continue to drink some alcohol while taking duloxetine. Street drugs Be careful if you are also using street drugs. Cannabis can make drowsiness, dizziness and confusion worse when taken with duloxetine. Duloxetine is likely to raise the effect of cocaine in your body, giving you a bigger reaction. Smoking Cigarette smoke affects the amount of duloxetine in your body. Tell your doctor if you smoke, so that you get the right dose for you.
If you re start smoking, you will probably need to increase it again. Go to your doctor for advice if you stop or start smoking. Can I take it with other medications? Duloxetine does not mix well with some other medicines and drugs. Are there any other interactions I should know about? The symptoms are any combination of the following: high fever agitation confusion trembling sweating diarrhoea loose poo fast heartbeat weird movements of your muscles You need to go to a hospital straight away if you get these symptoms.
For all these reasons, it may be a good idea to limit caffeine while taking duloxetine. Can I drive while taking it?
Duloxetine may also affect your eyesight and make you feel sleepy or dizzy. Do not worry - most people drive as normal while taking duloxetine. Can I take it if I am pregnant or breastfeeding? Pregnancy You should use good contraception when you are taking duloxetine. If you are planning a pregnancy, you should talk to your doctor about your options.
There may be a slight increase in the risk of miscarriage or premature birth. Post-natal If duloxetine is taken in the last five months of a pregnancy, it may cause a condition called persistent pulmonary hypertension of the new-born PPHN.
The newborn baby may also develop withdrawal effects that might include: irritability and crying a lot having difficulty sleeping or sucking These might not happen straight away, so you should look out for them over the first few days after the baby is born.
Breastfeeding A small amount of duloxetine is passed to the baby in breast milk. About duloxetine Duloxetine is an antidepressant medicine. Duloxetine comes as capsules and is only available on prescription. Help us improve our website Can you answer a quick question about your visit today?
Duloxetine normally takes 2 to 4 weeks to work. It may take longer if you're taking it for nerve pain. Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks.
If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent extra side effects. Duloxetine is also called by the brand names Cymbalta and Yentreve.
Duloxetine can be taken by adults aged 18 years and over. For stress urinary incontenince, duloxetine can only be used by women. To make sure it's safe for you, tell your doctor if you: have had an allergic reaction to duloxetine or any other medicines in the past have kidney or liver problems have a heart problem are taking or have taken other medicines for depression within the last 14 days have an eye condition called glaucoma - duloxetine can increase the pressure in your eye have or have had fits, manic episodes or bipolar disorder bruise easily are trying to become pregnant, are already pregnant, or you're breastfeeding.
How much will I take? How much you take will depend on what you're taking it for: depression - the starting dose is 60mg a day and can be increased to mg a day anxiety - the starting dose is 30mg a day and can be increased to 60mg a day nerve pain - the starting dose is 60mg a day and can be increased to 60mg twice a day stress urinary incontinence - the starting dose is 20mg twice a day and can be increased to 40mg twice a day after 2 weeks What if I forget to take it?
If you usually take duloxetine: once a day - take the missed dose as soon as you remember, unless it's less than 12 hours until your next dose, in which case skip the missed dose twice a day - take the missed dose as soon as you remember, unless it's less than 4 hours until your next dose, in which case skip the missed dose Never take 2 doses at the same time to make up for a forgotten one.
If you forget doses often, it may help to set an alarm to remind you. What if I take too much? Urgent advice: Call your doctor straight away if you take too much duloxetine and:. Common side effects These side effects happen in more than 1 in people. These are not all the side effects of duloxetine. For a full list, see the leaflet inside your medicines packet. Information: You can report any suspected side effect to the UK safety scheme.
What to do about: difficulty sleeping - try taking duloxetine first thing in the morning headaches - make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if they last longer than a week or are severe. If you begin to feel dizzy, lie down so you do not faint, then sit until you feel better.
Do not drive or use tools or machines if you feel dizzy, have muscle cramps or muscle pain, or if you just feel a bit shaky. If it lasts for more than a day or two, speak to your doctor as they may need to change your treatment. Try to exercise more regularly by going for a daily walk or run, for example.
If this does not help, talk to your pharmacist or doctor. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor first.
Make sure you take duloxetine in the morning with some food and try small, frequent sips of water if you're being sick to avoid dehydration. If this does not help, you may need to try a different type of antidepressant. Try taking duloxetine 1 hour before bedtime.
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